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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with WEGOVY [see Contraindications (4), Warnings and Precautions (5.1)]

Patients experiencing frequent vomiting should be monitored for signs of dehydration and may require temporary dose reduction or supportive care measures

However, patients with renal impairment may be at higher risk for dehydration from gastrointestinal side effects, which requires clinical vigilance

Rodent research indicates that GLP-1 agonists may reduce dopamine release in the nucleus accumbens in response to alcohol, thereby potentially diminishing its rewarding properties

[4] When taking Wegovy, patients should be aware of accompanying symptoms that warrant medical attention